Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22041544 | 1.00 | TDP1 (0.69) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL28343328 | 0.87 | POLB (0.69) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL28340849 | 0.87 | POLB (0.68) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL1753903 | 0.86 | TDP1 (0.79) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL28340810 | 0.85 | POLB (0.65) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL28340811 | 0.85 | POLB (0.65) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL9464627 | 0.84 | POLB (0.88) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL19329990 | 0.84 | TDP1 (0.60) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL30942024 | 0.83 | POLB (0.67) | TDP1POLBHTTHDAC6HDAC3 | |
| SCHEMBL22072359 | 0.83 | POLB (0.67) | TDP1POLBHTTHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219557-A | Preparation method of beta, gamma-unsaturated nitrile compound | 苏州大学 | 2024-12-31 | — | — | CN | claimed |
| CN-117447398-A | Synthesis method of cyclopentyl-substituted fatty amide | 南通大学 | 2024-01-26 | — | — | CN | claimed |
| CN-116478195-A | Method for synthesizing 1, 2-triboroalkane | 南京工业大学 | 2023-07-25 | — | — | CN | claimed |
| CN-113121373-B | Method for synthesizing chlorambucil | 南京工业大学 | 2022-06-24 | — | — | CN | claimed |
| CN-119219557-A | Preparation method of beta, gamma-unsaturated nitrile compound | 苏州大学 | 2024-12-31 | — | — | CN | disclosed |
| CN-119219557-A | Preparation method of beta, gamma-unsaturated nitrile compound | 苏州大学 | 2024-12-31 | — | — | CN | disclosed |
| CN-112552285-B | Synthesis method of 4- (2, 2-trichloroethyl) -beta-lactam derivative | 苏州大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-117447398-A | Synthesis method of cyclopentyl-substituted fatty amide | 南通大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-117417253-A | Method for preparing phenyl alkyl acid ester by alkyl olefin | 常州大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-117126135-A | Synthesis method of 3, 4-diaminobutyric acid derivative | 常州大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-116478195-A | Method for synthesizing 1, 2-triboroalkane | 南京工业大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-113121373-B | Method for synthesizing chlorambucil | 南京工业大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113121373-B | Method for synthesizing chlorambucil | 南京工业大学 | 2022-06-24 | — | — | CN | disclosed |