Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 5/20 | 0.32 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24522860 | 0.82 | KCNA3 (0.44) | TSHRALDH1A1CYP3A4HPGDKCNA3 | |
| SCHEMBL24522784 | 0.82 | GAA (0.38) | ALDH1A1HPGDKCNA3HDAC1CA9 | |
| SCHEMBL24522627 | 0.76 | PRKDC (0.41) | TSHRALDH1A1CYP3A4HPGDKCNA3 | |
| SCHEMBL24522875 | 0.76 | HDAC1 (0.39) | TSHRALDH1A1CYP3A4HPGDKCNA3 | |
| SCHEMBL24522988 | 0.76 | KCNA3 (0.62) | TSHRALDH1A1CYP3A4KCNA3CA12 | |
| SCHEMBL24522650 | 0.76 | KCNA3 (0.62) | TSHRALDH1A1CYP3A4KCNA3CA12 | |
| SCHEMBL24522975 | 0.76 | KCNA3 (0.62) | TSHRALDH1A1CYP3A4KCNA3CA12 | |
| SCHEMBL24522688 | 0.76 | KCNA3 (0.62) | TSHRALDH1A1CYP3A4KCNA3CA12 | |
| SCHEMBL24522872 | 0.74 | HDAC1 (0.37) | TSHRALDH1A1CYP3A4HPGDKCNA3 | |
| SCHEMBL24531635 | 0.72 | ALDH1A1 (0.51) | TSHRALDH1A1CYP3A4HPGDKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022128832-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |
| EP-4015512-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2022-06-22 | — | — | EP | disclosed |