Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24522650 | 0.85 | KCNA3 (0.62) | KCNA3ALDH1A1CYP3A4TSHRCA12 | |
| SCHEMBL24522975 | 0.85 | KCNA3 (0.62) | KCNA3ALDH1A1CYP3A4TSHRCA12 | |
| SCHEMBL24522688 | 0.85 | KCNA3 (0.62) | KCNA3ALDH1A1CYP3A4TSHRCA12 | |
| SCHEMBL24522988 | 0.85 | KCNA3 (0.62) | KCNA3ALDH1A1CYP3A4TSHRCA12 | |
| SCHEMBL24522862 | 0.84 | CA12 (0.48) | KCNA3ALDH1A1CYP3A4CA12CA1 | |
| SCHEMBL24531623 | 0.83 | POLB (0.43) | KCNA3TSHRCA12CA1CA9 | |
| SCHEMBL24522750 | 0.82 | TSHR (0.42) | KCNA3ALDH1A1CYP3A4TSHRCA12 | |
| SCHEMBL24522875 | 0.81 | HDAC1 (0.39) | KCNA3ALDH1A1CYP3A4TSHRCA12 | |
| SCHEMBL24522922 | 0.80 | KCNA3 (0.48) | KCNA3CA12CA1CA9HDAC1 | |
| SCHEMBL29054817 | 0.79 | HDAC1 (0.61) | KCNA3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022128832-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |
| EP-4015512-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2022-06-22 | — | — | EP | disclosed |