SCHEMBL24523723

SCHEMBL24523723

N#Cc1ccc2c3c(-c4ccccc4)c(-c4ccccc4)c(-c4ccccc4)c4c5ccc(C#N)cc5n(c2c1)c34

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
FASN P49327 1/20 0.43
CYP19A1 P11511 1/20 0.40
DPP4 P27487 2/20 0.39
CSF1R P07333 2/20 0.38
G6PD P11413 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24523802 0.90 DPP4 (0.39) MEN1KMT2AFASNDPP4CSF1R
SCHEMBL24523721 0.87 ALDH1A1 (0.41) MEN1KMT2AFASNDPP4CSF1R
SCHEMBL24523799 0.87 PTGDR2 (0.41) MEN1KMT2AFASNCYP19A1DPP4
SCHEMBL24523795 0.84 PTGDR2 (0.39) MEN1KMT2AFASNCYP19A1PTGDR2
SCHEMBL24523847 0.83 CA1 (0.40) MEN1KMT2AG6PD
SCHEMBL24601758 0.83 CA1 (0.40) MEN1KMT2AG6PD
SCHEMBL24523798 0.81 PTGDR2 (0.42) MEN1KMT2AFASNCYP19A1DPP4
SCHEMBL20821364 0.81 MEN1 (0.40) MEN1KMT2AFASNCYP19A1DPP4
SCHEMBL24523719 0.80 MEN1 (0.39) MEN1KMT2AFASNCYP19A1DPP4
SCHEMBL24523724 0.79 GABRA1 (0.39) MEN1KMT2AFASNCYP19A1G6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022129116-A1 INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed