Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24524311 | 0.94 | AR (0.31) | PNMTKDM4EALDH1A1 | |
| SCHEMBL24524359 | 0.87 | MAOA (0.36) | KDM4EALDH1A1 | |
| SCHEMBL24524234 | 0.84 | — | — | |
| SCHEMBL24524005 | 0.84 | CA1 (0.31) | ELANE | |
| SCHEMBL24524275 | 0.83 | KCNA3 (0.30) | — | |
| SCHEMBL24524242 | 0.80 | SSTR2 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL24524495 | 0.79 | MAOA (0.33) | KDM4EALDH1A1 | |
| SCHEMBL24524356 | 0.79 | KDM4E (0.33) | KDM4EALDH1A1IMPDH2 | |
| SCHEMBL24523731 | 0.76 | IMPDH2 (0.33) | KDM4EALDH1A1IMPDH2 | |
| SCHEMBL26346197 | 0.75 | KDM4E (0.30) | KDM4EALDH1A1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |