Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24524513 | 0.96 | KDM4E (0.37) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL30054908 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL30047273 | 0.72 | SMN1; SMN2 (0.40) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL30106771 | 0.72 | SMN1; SMN2 (0.43) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL13451350 | 0.71 | PARP1 (0.33) | ALDH1A1MAPTHSD17B10ALOX15LMNA | |
| SCHEMBL29386169 | 0.71 | BCL2L1 (0.47) | KDM4EALDH1A1MAPTHSD17B10ALOX15 | |
| SCHEMBL19679240 | 0.71 | BCL2L1 (0.47) | KDM4EALDH1A1MAPTHSD17B10ALOX15 | |
| SCHEMBL6228564 | 0.71 | MEN1 (0.45) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL3345163 | 0.69 | PARP10 (0.39) | KDM4EALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL24373453 | 0.69 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |