Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4263061 | 0.96 | MEN1 (0.45) | MEN1TTRALBKMT2AXDH | |
| SCHEMBL11814822 | 0.81 | — | — | |
| SCHEMBL6002728 | 0.81 | XDH (0.42) | MEN1TTRALBKMT2AXDH | |
| SCHEMBL19679244 | 0.77 | XDH (0.49) | MEN1TTRALBKMT2AXDH | |
| SCHEMBL26484276 | 0.77 | XDH (0.40) | XDHSLC22A12ALDH1A1MAPTHPGD | |
| SCHEMBL11814510 | 0.73 | XDH (0.33) | MEN1KMT2AXDHSLC22A12MAPT | |
| SCHEMBL24373453 | 0.72 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL29479151 | 0.72 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL4262554 | 0.72 | XDH (0.58) | XDHSLC22A12ALDH1A1HPGDCYP11B2 | |
| SCHEMBL24524553 | 0.71 | KDM4E (0.40) | ALDH1A1MAPTHPGDAPOBEC3GCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182269-A1 | Process for the preparation of 3-cyano-1-naphthoic acid and some analogues thereof | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | US | disclosed |
| EP-1517884-A1 | A PROCESS FOR THE PREPARATION OF 3-CYANO-1-NAPHTHOIC ACID AND SOME ANALOGUES THEREOF | AstraZeneca AB (SE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000792-A1 | A PROCESS FOR THE PREPARATION OF 3-CYANO-1-NAPHTHOIC ACID AND SOME ANALOGUES THEREOF | ASTRAZENECA AB (SE) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182269-A1 | Process for the preparation of 3-cyano-1-naphthoic acid and some analogues thereof | CYP8B1, CYP51A1, NISCH | MEN1 1011/4885TTR 1691/4885ALB 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.