Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830004 | 0.71 | — | — | |
| SCHEMBL17830005 | 0.71 | — | — | |
| SCHEMBL24370195 | 0.71 | — | — | |
| SCHEMBL60463 | 0.68 | — | — | |
| SCHEMBL11921 | 0.68 | — | — | |
| SCHEMBL11926 | 0.68 | — | — | |
| SCHEMBL1760663 | 0.66 | CYP1A2 (0.64) | CYP1A2ADRA2A | |
| Bromide SCHEMBL27865865 | 0.66 | CYP1A2 (0.53) | CYP1A2ADRA2A | |
| SCHEMBL3476022 | 0.66 | CYP1A2 (0.64) | CYP1A2ADRA2A | |
| SCHEMBL25008975 | 0.66 | HTR2A (0.41) | ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133215-A1 | CDK INHIBITORS AND THEIR USE AS PHARMACEUTICALS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-06-23 | — | — | WO | disclosed |