Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24090220 | 0.89 | HTR2A (0.39) | HTR2AHTR2CDRD2SIGMAR1 | |
| SCHEMBL13564385 | 0.82 | HTR6 (0.42) | HTR2AHTR2CDRD2SIGMAR1 | |
| SCHEMBL25799682 | 0.82 | SIGMAR1 (0.43) | DRD2SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL27361464 | 0.80 | CYP1A2 (0.38) | CHRM2CHRM4CHRM5CHRM3 | |
| Ammonia Solution, Strong SCHEMBL11490821 | 0.80 | HTR6 (0.41) | HTR2AHTR2CDRD2SIGMAR1NPC1 | |
| SCHEMBL22421710 | 0.79 | KDM4E (0.35) | — | |
| SCHEMBL19941939 | 0.75 | DRD2 (0.41) | HTR2AHTR2CDRD2SIGMAR1 | |
| SCHEMBL11833857 | 0.74 | PNMT (0.36) | HTR2AHTR2CDRD2SIGMAR1 | |
| SCHEMBL26027252 | 0.74 | — | — | |
| SCHEMBL1117934 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023015200-A1 | AMNIOTIC FLUID STABILIZED COMPOSITIONS AND METHODS FOR IN UTERO DELIVERY OF THERAPEUTIC AGENTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2023-02-09 | — | — | WO | disclosed |