Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528058 | 0.89 | KDM4E (0.43) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL24528406 | 0.86 | KDM4E (0.41) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL26329772 | 0.84 | KDM4E (0.47) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL24527936 | 0.84 | KDM4E (0.44) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL26329761 | 0.84 | KDM4E (0.50) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL24527747 | 0.84 | KDM4E (0.44) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL24527994 | 0.82 | KDM4E (0.45) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL24528000 | 0.81 | KDM4E (0.44) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL24527798 | 0.81 | KDM4E (0.46) | KDM4EATML3MBTL1DYRK1ACDK4 | |
| SCHEMBL21454348 | 0.81 | L3MBTL1 (0.46) | KDM4EATML3MBTL1DYRK1ACDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129113-A1 | NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |