Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17265103 | 0.89 | MAOA (0.48) | KDM4EATML3MBTL1MAOAMAOB | |
| SCHEMBL17265102 | 0.89 | MAOA (0.48) | KDM4EATML3MBTL1MAOAMAOB | |
| SCHEMBL24528050 | 0.89 | KDM4E (0.44) | KDM4EATML3MBTL1MAOAMAOB | |
| SCHEMBL16356754 | 0.85 | KDM4E (0.50) | KDM4EATML3MBTL1MAOAMAOB | |
| SCHEMBL5021391 | 0.85 | KDM4E (0.50) | KDM4EATML3MBTL1MAOAMAOB | |
| SCHEMBL24528060 | 0.85 | DYRK1A (0.36) | KDM4EATML3MBTL1DYRK1ACYP1A2 | |
| SCHEMBL24527994 | 0.84 | KDM4E (0.45) | KDM4EATML3MBTL1MAOAMAOB | |
| SCHEMBL17146739 | 0.83 | KDM4E (0.56) | KDM4EATML3MBTL1ALDH1A1HPGD | |
| SCHEMBL24528000 | 0.83 | KDM4E (0.44) | KDM4EATML3MBTL1MAOAMAOB | |
| SCHEMBL24527747 | 0.83 | KDM4E (0.44) | KDM4EATML3MBTL1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129113-A1 | NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |