Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528599 | 0.99 | KDM4E (0.33) | KDM4EALDH1A1MAPK1ATMLMNA | |
| SCHEMBL24528695 | 0.97 | KDM4E (0.34) | KDM4EALDH1A1MAPK1ATMLMNA | |
| SCHEMBL24528677 | 0.96 | KDM4E (0.34) | KDM4EALDH1A1MAPK1LMNATLR9 | |
| SCHEMBL29681045 | 0.96 | KDM4E (0.37) | KDM4EALDH1A1MAPK1ATMLMNA | |
| SCHEMBL24528596 | 0.96 | KDM4E (0.37) | KDM4EALDH1A1MAPK1ATMLMNA | |
| SCHEMBL29680746 | 0.94 | KDM4E (0.37) | KDM4EALDH1A1MAPK1ATMLMNA | |
| SCHEMBL24528512 | 0.94 | KDM4E (0.37) | KDM4EALDH1A1MAPK1ATMLMNA | |
| SCHEMBL24528652 | 0.93 | KDM4E (0.32) | KDM4EALDH1A1LMNAPDE4B | |
| SCHEMBL24528627 | 0.88 | ALDH1A1 (0.36) | KDM4EALDH1A1RAD52POLB | |
| SCHEMBL24528689 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |