Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27191476 | 0.98 | KDM1A (0.48) | KDM1ADRD2DRD4BCHESHBG | |
| Bromide SCHEMBL30645337 | 0.98 | KDM1A (0.48) | KDM1ADRD2DRD4BCHESHBG | |
| SCHEMBL8514438 | 0.84 | BCHE (0.44) | KDM1ADRD2DRD4BCHEKDM4E | |
| SCHEMBL8513919 | 0.81 | BCHE (0.44) | KDM1ADRD2DRD4BCHEKDM4E | |
| Bromide SCHEMBL9531808 | 0.79 | KDM1A (0.47) | KDM1ADRD2DRD4BCHEKDM4E | |
| SCHEMBL10837762 | 0.79 | HTR2C (0.52) | KDM1ACA1CA2CA7CA9 | |
| SCHEMBL10349438 | 0.78 | DRD2 (0.62) | KDM1ADRD2DRD4BCHEKDM4E | |
| SCHEMBL1009943 | 0.78 | PRCP (0.64) | KDM4E | |
| Bromide SCHEMBL11619182 | 0.77 | KDM1A (0.42) | KDM1ADRD2DRD4BCHEKDM4E | |
| SCHEMBL8469298 | 0.77 | KMT2A (0.48) | KDM1ADRD2DRD4BCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129925-A1 | NOVEL BIFUNCTIONAL MOLECULES FOR TARGETED PROTEIN DEGRADATION | AMPHISTA THERAPEUTICS LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |