SCHEMBL24529092

SCHEMBL24529092

Cc1c2nc3c(nc2c(Br)c2nc4c(nc12)c(=O)c1ccccc14)c(=O)c1ccccc13

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
BLM P54132 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAOA P21397 1/20 0.33
PARP1 P09874 4/20 0.33
PDE7A Q13946 1/20 0.33
MAP3K5 Q99683 1/20 0.32
TNKS2 Q9H2K2 2/20 0.32
ELANE P08246 2/20 0.32
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 2/20 0.31
TNKS O95271 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24529093 1.00 MEN1 (0.36) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL31438759 0.74 MEN1 (0.45) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL1755055 0.70 MYC (0.41) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL1755060 0.70 MYC (0.41) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL31319840 0.67 MAPT (0.43) KMT2APOLBMAPTBLMTDP1
SCHEMBL668870 0.65 ALDH1A1 (0.50) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL208269 0.64 HSP90AA1 (0.40) MEN1KMT2AALDH1A1CYP1A2KDM4E
SCHEMBL14572504 0.64 MEN1 (0.35) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL16169847 0.63 LMNA (0.40) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL12355748 0.62 MAPT (0.48) MEN1KMT2ALMNAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022129595-A1 PHOTOACTIVE MATERIAL CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2022-06-23 WO disclosed