Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 8/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 10/20 | 0.36 |
| ▸ | CD63 | P08962 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24386989 | 0.90 | HCRTR2 (0.41) | HCRTR2PDE3BPDE3ASYKCD63 | |
| SCHEMBL24529251 | 0.85 | HCRTR2 (0.36) | HCRTR2PDE3BPDE3A | |
| SCHEMBL24529427 | 0.81 | HCRTR2 (0.33) | HCRTR2 | |
| SCHEMBL24529263 | 0.81 | HCRTR2 (0.41) | HCRTR2SYKCD63 | |
| SCHEMBL24529568 | 0.80 | HCRTR2 (0.57) | HCRTR2PDE3BPDE3ASYKCD63 | |
| SCHEMBL24529162 | 0.77 | HCRTR2 (0.60) | HCRTR2PDE3BPDE3ASYKCD63 | |
| SCHEMBL27180727 | 0.77 | HCRTR2 (0.60) | HCRTR2PDE3BPDE3ASYKCD63 | |
| SCHEMBL29723690 | 0.77 | HCRTR2 (0.60) | HCRTR2PDE3BPDE3ASYKCD63 | |
| SCHEMBL29723788 | 0.74 | HCRTR2 (0.50) | HCRTR2PDE3BPDE3ASYKCD63 | |
| SCHEMBL24386988 | 0.74 | ALDH1A1 (0.38) | HCRTR2PDE3BPDE3ASYKCD63 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |