Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 8/20 | 0.72 |
| ▸ | RET | P07949 | 4/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24529170 | 0.84 | HCRTR2 (1.00) | HCRTR2RETTGFBR1MCHR1 | |
| SCHEMBL27181016 | 0.84 | HCRTR2 (1.00) | HCRTR2RETTGFBR1MCHR1 | |
| SCHEMBL27181021 | 0.84 | HCRTR2 (1.00) | HCRTR2RETTGFBR1MCHR1 | |
| SCHEMBL24529288 | 0.77 | HCRTR2 (0.53) | HCRTR2PTGESMGLL | |
| SCHEMBL24529700 | 0.77 | HCRTR2 (0.52) | HCRTR2PTGES | |
| SCHEMBL24529380 | 0.74 | HCRTR2 (0.42) | HCRTR2PTGES | |
| SCHEMBL24529668 | 0.74 | HCRTR2 (0.58) | HCRTR2RETTGFBR1MCHR1 | |
| SCHEMBL29723804 | 0.74 | HCRTR2 (0.58) | HCRTR2RETTGFBR1MCHR1 | |
| SCHEMBL29723579 | 0.74 | HCRTR2 (0.58) | HCRTR2RETTGFBR1MCHR1 | |
| SCHEMBL24529484 | 0.74 | HCRTR2 (0.58) | HCRTR2RETTGFBR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |