Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24529293 | 0.80 | — | — | |
| SCHEMBL24387233 | 0.77 | PGK1 (0.38) | PGK1 | |
| SCHEMBL29723704 | 0.76 | S100A9 (0.33) | — | |
| SCHEMBL24386870 | 0.76 | S100A9 (0.33) | — | |
| Hydrochloric Acid SCHEMBL29749958 | 0.75 | KMT2A (0.34) | — | |
| SCHEMBL17845775 | 0.70 | — | — | |
| SCHEMBL24387206 | 0.70 | HTR2A (0.40) | PGK1 | |
| Hydrochloric Acid SCHEMBL29750002 | 0.69 | HTR2A (0.39) | PGK1 | |
| SCHEMBL29749999 | 0.67 | CCR4 (0.41) | — | |
| SCHEMBL376592 | 0.67 | CCR4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132696-A1 | UREA OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |