⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956369 | 0.88 | — | — | |
| SCHEMBL528874 | 0.86 | ADH1A (0.54) | — | |
| SCHEMBL18570188 | 0.86 | ADH1A (0.54) | — | |
| SCHEMBL14616081 | 0.75 | — | — | |
| SCHEMBL2874295 | 0.67 | — | — | |
| SCHEMBL22810795 | 0.63 | — | — | |
| SCHEMBL308431 | 0.62 | — | — | |
| SCHEMBL1750914 | 0.62 | — | — | |
| SCHEMBL6006488 | 0.62 | ADH1A (0.94) | — | |
| SCHEMBL6005197 | 0.61 | ADH1A (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013153-B2 | Substituted pyrimidine kinase inhibitors | JANSSEN PHARMACEUTICA, N.V. (BE) | 2011-09-06 | — | — | US | claimed |
| CN-101501022-A | Benzimidazole derivatives as cannabinoid receptor 1 receptor antagonists | ASTRAZENECA AB (SE) | 2009-08-05 | — | — | CN | claimed |
| CN-101472917-A | Benzimidazole 5-sulfonamide derivatives as cannabinoid 1 (CB1) receptor ligands | ASTRAZENECA AB (SE) | 2009-07-01 | — | — | CN | claimed |
| US-20070254896-A1 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-11-01 | — | — | US | claimed |
| WO-2007109783-A2 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-09-27 | — | — | WO | claimed |
| CN-1188429-C | Natural rubber latex and nutual rubber containing viscosity stabilizing agent and production method thereof | BRIDGESTON CORP (JP) | 2005-02-09 | — | — | CN | claimed |
| CN-1330083-A | Natural rubber latex and nutual rubber containing viscosity stabilizing agent and production method thereof | BRIDGESTON CORP (JP) | 2002-01-09 | — | — | CN | claimed |
| CN-113149961-B | Azabicyclo-substituted triazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-113149961-A | Azabicyclo-substituted triazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-109071492-B | Azabicyclo-substituted triazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112055713-A | Compounds and compositions for treating diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-111499580-A | Substituted diaminocarboxamides and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111471021-A | Substituted diaminocarboxamides and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-101384591-A | Antiviral compounds | ABBOTT LAB (US) | 2009-03-11 | — | — | CN | disclosed |
| CN-101253166-A | Sulfonamide compound | ASAHI KASEI PHARMA CORP (JP) | 2008-08-27 | — | — | CN | disclosed |
| US-20070254896-A1 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-11-01 | — | — | US | disclosed |
| WO-2007109783-A2 | SUBSTITUTED PYRIMIDINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-09-27 | — | — | WO | disclosed |
| CN-1188429-C | Natural rubber latex and nutual rubber containing viscosity stabilizing agent and production method thereof | BRIDGESTON CORP (JP) | 2005-02-09 | — | — | CN | disclosed |
| CN-1330083-A | Natural rubber latex and nutual rubber containing viscosity stabilizing agent and production method thereof | BRIDGESTON CORP (JP) | 2002-01-09 | — | — | CN | disclosed |
| CN-1251589-A | Substituted triazolopyridazine derivatives as ligands for GABA receptors | MERCK SHARP & DOHME (GB) | 2000-04-26 | — | — | CN | disclosed |