Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 12/20 | 0.54 |
| ▸ | ADH1C | P00326 | 9/20 | 0.52 |
| ▸ | ADH4 | P08319 | 3/20 | 0.50 |
| ▸ | ADH1B | P00325 | 3/20 | 0.46 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528874 | 1.00 | ADH1A (0.54) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL3956369 | 0.97 | — | — | |
| SCHEMBL27719489 | 0.95 | — | — | |
| SCHEMBL27845046 | 0.91 | ADH1A (0.46) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL2453051 | 0.86 | — | — | |
| SCHEMBL28057896 | 0.75 | ADH1A (0.33) | ADH1AADH1CADH4 | |
| SCHEMBL27121722 | 0.74 | ADH1A (0.37) | ADH1AADH1CADH4ADH1BPHGDH | |
| SCHEMBL28005038 | 0.73 | APLNR (0.38) | ADH1AADH1CADH4ADH1B | |
| SCHEMBL28040278 | 0.73 | APLNR (0.38) | ADH1AADH1CADH4ADH1B | |
| SCHEMBL10012570 | 0.72 | ADH1A (0.94) | ADH1AADH1CADH4ADH1BADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2948434-B1 | SQUARIC DERIVATIVES FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2017-03-01 | — | — | EP | disclosed |