SCHEMBL24531192

SCHEMBL24531192

CNC(=O)[C@H](CCCCNC(=N)N)NC

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ SIRT6 Q8N6T7 1/20 0.38
▸ SIRT1 Q96EB6 1/20 0.38
▸ NPY4R P50391 10/20 0.36
▸ NPY1R P25929 7/20 0.36
▸ NPY2R P49146 5/20 0.36
▸ NPY5R Q15761 5/20 0.36
▸ DPP7 Q9UHL4 2/20 0.36
▸ GNAI3 P08754 1/20 0.35
▸ GNAO1 P09471 1/20 0.35
▸ GNAI1 P63096 1/20 0.35
▸ SIRT5 Q9NXA8 1/20 0.34
▸ RRM1 P23921 1/20 0.33
▸ FOLH1 Q04609 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21096857 0.86 SIRT6 (0.38) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL19487472 0.85 ALOX15 (0.39) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL29888878 0.85 FOLH1 (0.43) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL350358 0.85 FOLH1 (0.43) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL18356744 0.85 ALOX15 (0.39) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL8663352 0.85 FOLH1 (0.43) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL25857221 0.84 NPY4R (0.42) SIRT6SIRT1NPY4RNPY1RNPY2R
SCHEMBL27115457 0.83 DPP7 (0.50) SIRT6SIRT1DPP7GNAI3GNAO1
SCHEMBL24531193 0.83 C3AR1 (0.38) MEN1KMT2ASIRT6SIRT1DPP7
SCHEMBL30483974 0.83 NPY4R (0.53) SIRT6SIRT1NPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220193210-A1 THERAPEUTICS FOR AUTOIMMUNE KIDNEY DISEASE: SYNTHETIC ANTIGENS DANMARKS TEKNISKE UNIVERSITET (DK) 2022-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220193210-A1 THERAPEUTICS FOR AUTOIMMUNE KIDNEY DISEASE: SYNTHETIC ANTIGENS SSB, HAVCR2, CD47 ALOX15 3289/4885MEN1 1723/4885CYP1A2 4630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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