SCHEMBL2453172

SCHEMBL2453172

C=COCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
PKM P14618 1/20 0.60
RARB P10826 5/20 0.58
HTT P42858 3/20 0.54
MAPK1 P28482 2/20 0.50
TSHR P16473 2/20 0.50
TP53 P04637 1/20 0.50
PLA2G4B P0C869 2/20 0.49
SRD5A2 P31213 1/20 0.48
HSD17B10 Q99714 2/20 0.48
USP2 O75604 1/20 0.48
ALOX15 P16050 1/20 0.48
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL718569 0.95 ALDH1A1 (0.66) ALDH1A1L3MBTL1PKMRARBHTT
SCHEMBL941435 0.94 ALDH1A1 (0.64) ALDH1A1L3MBTL1PKMRARBHTT
SCHEMBL2449697 0.88 ALDH1A1 (0.57) ALDH1A1L3MBTL1PKMRARBHTT
SCHEMBL8680422 0.87 ALDH1A1 (0.69) ALDH1A1L3MBTL1PKMRARBHTT
SCHEMBL8569877 0.87 PKM (0.78) ALDH1A1L3MBTL1PKMRARBHTT
SCHEMBL2880470 0.86 HTT (0.67) ALDH1A1L3MBTL1PKMRARBHTT
SCHEMBL8678922 0.86 HTT (0.67) ALDH1A1L3MBTL1PKMRARBHTT
SCHEMBL4351247 0.86 HTT (0.67) ALDH1A1L3MBTL1PKMRARBHTT
SCHEMBL8678888 0.86 HTT (0.67) ALDH1A1L3MBTL1PKMRARBHTT
SCHEMBL5983886 0.85 CA1 (0.44) ALDH1A1L3MBTL1PKMRARBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006351-B1 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM NIPPON OIL CORP (JP) 2011-10-12 EP disclosed
EP-1422255-B1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY NIPPON OIL CORP (JP) 2011-09-28 EP disclosed
US-20100208182-A1 METHOD FOR MANUFACTURING OPTICAL FILM NIPPON OIL CORPORATION (JP) 2010-08-19 US disclosed
US-7763182-B2 Liquid crystalline composition with improved adhesivity, liquid crystal film comprising the composition, and liquid crystal display device equipped with the film NIPPON OIL CORPORATION (JP) 2010-07-27 US disclosed
EP-2202546-A1 METHOD FOR PRODUCING OPTICAL FILM Nippon Oil Corporation (JP) 2010-06-30 EP disclosed
US-20090208673-A1 Liquid Crystalline Composition with Improved Adhesivity, Liquid Crystal Film Comprising the Composition, and Liquid Crystal Display Device Equipped with the Film NIPPON OIL CORPORATION (JP) 2009-08-20 US disclosed
EP-2006351-A9 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM Nippon Oil Corporation (JP) 2009-07-01 EP disclosed
EP-2006351-A2 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM Nippon Oil Corporation (JP) 2008-12-24 EP disclosed
US-6894141-B2 Main chain type liquid crystalline polyester, liquid crystalline composition, method for producing liquid crystal film and optical film, and display having optical film NIPPON OIL CORPORATION (JP) 2005-05-17 US disclosed
US-20040171788-A1 Main chain type liquid crystal polyester, liquid crystalline composition, method for producing liquid crystal film, optical film and display NOBLE VENTURE FINANCE I LIMITED (GB) 2004-09-02 US disclosed
EP-1422255-A1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY Nippon Oil Corporation (JP) 2004-05-26 EP disclosed