Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2453021 | 0.94 | L3MBTL1 (0.43) | L3MBTL1BAZ1ARAB9AMEN1KMT2A | |
| SCHEMBL2454628 | 0.90 | L3MBTL1 (0.47) | L3MBTL1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL2452649 | 0.78 | ALDH1A1 (0.47) | L3MBTL1RAB9AMEN1KMT2AHTT | |
| SCHEMBL2457208 | 0.73 | KDR (0.37) | L3MBTL1HTTMAPT | |
| SCHEMBL2455971 | 0.71 | L3MBTL1 (0.42) | L3MBTL1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL27520964 | 0.70 | L3MBTL1 (0.59) | L3MBTL1RAB9AMEN1KMT2AHTT | |
| SCHEMBL14267699 | 0.70 | KMT2A (0.69) | L3MBTL1RAB9AMEN1KMT2AHTT | |
| SCHEMBL6814707 | 0.66 | CYP1A2 (0.66) | L3MBTL1RAB9AMEN1KMT2AHTT | |
| SCHEMBL2453229 | 0.66 | KDR (0.51) | RAB9AMEN1KMT2ACASP3SENP7 | |
| SCHEMBL3138660 | 0.65 | TDP1 (0.53) | RAB9AMEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237620-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237620-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | BRAF, NR3C2, RAF1 | L3MBTL1 3976/4885BAZ1A 227/4885RAB9A 1543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.