Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.50 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.39 |
| ▸ | KDM5C | P41229 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KDM6B | O15054 | 3/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL30396653 | 0.83 | — | — | |
| Glycolic Acid SCHEMBL8676747 | 0.83 | FFAR3 (0.33) | FFAR3OR51E2ALDH1A1AKR1B1 | |
| Propylene Oxide SCHEMBL7051815 | 0.82 | — | — | |
| Propylene Oxide SCHEMBL19329203 | 0.82 | MAPK1 (0.36) | LMNASUCNR1FFAR3MAPK1ALDH1A1 | |
| Propylene Oxide SCHEMBL21222708 | 0.82 | MAPK1 (0.36) | LMNASUCNR1FFAR3MAPK1ALDH1A1 | |
| Propylene Oxide SCHEMBL8086427 | 0.82 | GABRP (0.45) | PHF8KDM2AFOLH1 | |
| Propionic Acid SCHEMBL11355471 | 0.81 | FFAR3 (0.53) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Chloroacetic Acid SCHEMBL28654977 | 0.81 | — | — | |
| Stearic Acid SCHEMBL3386955 | 0.80 | GPR84 (0.68) | LMNAOR51E2SLC22A6ALDH1A1TSHR | |
| Acetic Acid SCHEMBL3810967 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805359-A | Lubricating oil composition for air compressor, method for lubricating air compressor, and air compressor | 出光兴产株式会社 | 2021-05-14 | — | — | CN | disclosed |
| EP-1835351-B1 | Toner, method of manufacturing the same, image forming apparatus, process cartridge and image forming method | RICOH CO LTD (JP) | 2011-09-07 | — | — | EP | disclosed |
| US-20070218382-A1 | TONER AND METHOD OF MANUFACTURING THE SAME | RICOH COMPANY, LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1835351-A1 | Toner, method of manufacturing the same, image forming apparatus, process cartridge and image forming method | Ricoh Company, Ltd. (JP) | 2007-09-19 | — | — | EP | disclosed |