Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43720 | 0.92 | TSHR (0.34) | TSHR | |
| SCHEMBL768869 | 0.87 | TSHR (0.45) | TSHRTDP1 | |
| SCHEMBL27362202 | 0.85 | TSHR (0.30) | TSHR | |
| SCHEMBL13698947 | 0.84 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL13069250 | 0.83 | PSMB8 (0.35) | — | |
| SCHEMBL26014291 | 0.83 | — | — | |
| SCHEMBL26014299 | 0.83 | — | — | |
| SCHEMBL1728021 | 0.82 | PSMB8 (0.32) | — | |
| SCHEMBL17430393 | 0.81 | KMT2A (0.33) | — | |
| Mercaptopropionic Acid SCHEMBL1014492 | 0.81 | TSHR (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022130046-A1 | N-1 BRANCHED IMIDAZOQUINOLINES, CONJUGATES THEREOF, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-06-23 | — | — | WO | disclosed |