SCHEMBL768869

SCHEMBL768869

O=C(O)CCSSCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
LMNA P02545 2/20 0.34
KMT2A Q03164 2/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PSMB8 P28062 1/20 0.33
PSMB5 P28074 1/20 0.33
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.31
IMPDH1 P20839 1/20 0.30
MGLL Q99685 1/20 0.30
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43720 0.95 TSHR (0.34) TSHRLMNAPSMB8PSMB5MGLL
Mercaptopropionic Acid SCHEMBL1014492 0.91 TSHR (0.35) TSHRPSMB8PSMB5
SCHEMBL27362202 0.88 TSHR (0.30) TSHRLMNAPSMB8PSMB5
SCHEMBL24533288 0.87 TSHR (0.32) TSHRTDP1
SCHEMBL13698947 0.87 SMN1; SMN2 (0.33) KMT2APSMB8PSMB5
SCHEMBL43575 0.85 EGLN1 (0.36) LMNAKMT2APSMB8PSMB5MAPK1
SCHEMBL26014291 0.85
SCHEMBL26014299 0.85
SCHEMBL1728021 0.85 PSMB8 (0.32) LMNAPSMB8PSMB5
SCHEMBL17430393 0.84 KMT2A (0.33) LMNAKMT2APSMB8PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3808760-A1 COMPOUND COMPRISING SUBSTANCE HAVING AFFINITY FOR ANTIBODY, CLEAVAGE SITE AND REACTIVE GROUP, OR SALT THEREOF AJINOMOTO CO., INC. (JP) 2021-04-21 EP disclosed
US-20190011442-A1 METHOD FOR DETECTING SUBSTANCE OF INTEREST, METHOD FOR QUANTIFYING SUBSTANCE OF INTEREST, KIT, AND METHOD FOR PREPARING REAGENT FURUKAWA ELECTRIC CO., LTD. (JP) 2019-01-10 US disclosed
US-20180348228-A1 Method of Determining Quantity of Objects to be Detected in Specimen ORTHO CLINICAL DIAGNOSTICS KK (JP) 2018-12-06 US disclosed
US-9714942-B2 Detection method and determination method for detection target JNC CORPORATION (JP) 2017-07-25 US disclosed
EP-2237036-B1 DETECTION METHOD AND DETERMINATION METHOD FOR DETECTION TARGET ORTHO CLINICAL DIAGNOSTICS KABUSHIKI KAISHA (JP) 2015-11-11 EP disclosed
US-9063144-B2 Detection method and quantification method for target substance JNC CORPORATION (JP) 2015-06-23 US disclosed
EP-2546653-B1 Electrode for Measuring Glycoprotein and Preparation Method Thereof LG ELECTRONICS INC (KR) 2015-04-15 EP disclosed
US-8841651-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2014-09-23 US disclosed
US-8815518-B2 Kit for detection/quantification of analyte, and method for detection/quantification of analyte JNC CORPORATION (JP) 2014-08-26 US disclosed
EP-2037272-B1 KIT FOR DETECTION/QUANTIFICATION OF ANALYTE, AND METHOD FOR DETECTION/QUANTIFICATION OF ANALYTE JNC CORP (JP) 2013-09-18 EP disclosed
US-20130015062-A1 ELECTRODE FOR MEASURING GLYCOPROTEIN AND PREPARATION METHOD THEREOF LG ELECTRONICS INC. (KR) 2013-01-17 US disclosed
EP-2546653-A1 Electrode for Measuring Glycoprotein and Preparation Method Thereof LG Electronics Inc. (KR) 2013-01-16 EP disclosed
US-20120070912-A1 DETECTION METHOD AND QUANTIFICATION METHOD FOR TARGET SUBSTANCE ORTHO-CLINICAL DIAGNOSTICS KABUSHIKI KAISHA (JP) 2012-03-22 US disclosed
US-20100330688-A1 DETECTION METHOD AND DETERMINATION METHOD FOR DETECTION TARGET ORTHO-CLINICAL DIAGNOSTICS KABUSHIKI KAISHA (JP) 2010-12-30 US disclosed
EP-2237036-A1 DETECTION METHOD AND DETERMINATION METHOD FOR DETECTION TARGET Ortho-clinical Diagnostics Kabushiki Kaisha (JP) 2010-10-06 EP disclosed
US-20100062433-A1 KIT FOR DETECTION/QUANTIFICATION OF ANALYTE, AND METHOD FOR DETECTION/QUANTIFICATION OF ANALYTE CHISSO CORPORATION (JP) 2010-03-11 US disclosed
EP-2037272-A1 KIT FOR DETECTION/QUANTIFICATION OF ANALYTE, AND METHOD FOR DETECTION/QUANTIFICATION OF ANALYTE CHISSO CORPORATION (JP) 2009-03-18 EP disclosed
WO-1989006701-A1 THIOL-REACTIVE OLIGONUCLEOTIDE INTERMEDIATES AND PROCESSES FOR CONJUGATION OF OLIGONUCLEOTIDES WITH ENZYMES MICROPROBE CORPORATION (US) 1989-07-27 WO disclosed