Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL768869 | 0.91 | TSHR (0.45) | TSHRPSMB8PSMB5 | |
| SCHEMBL43720 | 0.89 | TSHR (0.34) | TSHRPSMB8PSMB5 | |
| SCHEMBL2454641 | 0.84 | PSMB8 (0.33) | ACEPSMB8PSMB5 | |
| SCHEMBL27362202 | 0.83 | TSHR (0.30) | TSHRPSMB8PSMB5 | |
| SCHEMBL24533288 | 0.81 | TSHR (0.32) | TSHR | |
| SCHEMBL13698947 | 0.81 | SMN1; SMN2 (0.33) | PSMB8PSMB5 | |
| SCHEMBL43575 | 0.80 | EGLN1 (0.36) | PSMB8PSMB5 | |
| SCHEMBL26014291 | 0.80 | — | — | |
| SCHEMBL26014299 | 0.80 | — | — | |
| SCHEMBL1728021 | 0.80 | PSMB8 (0.32) | PSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130550-A1 | PROTEIN MONOMER, PROTEIN POLYMER OBTAINED FROM SAID MONOMER, AND DEVICE THAT CONTAINS THEM | OSAKA UNIVERSITY (JP) | 2011-06-02 | — | — | US | disclosed |
| EP-2272867-A1 | PROTEIN MONOMER, PROTEIN POLYMER OBTAINED FROM SAID MONOMER, AND DEVICE THAT CONTAINS THEM | Osaka University (JP) | 2011-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130550-A1 | PROTEIN MONOMER, PROTEIN POLYMER OBTAINED FROM SAID MONOMER, AND DEVICE THAT CONTAINS THEM | MAX, MLX, MRPL21 | TSHR 2451/4885ACE 1590/4885PSMB8 931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.