Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357637 | 0.84 | CYP3A4 (0.61) | USP2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL3870979 | 0.82 | KMT2A (0.58) | USP2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL24533634 | 0.81 | TSHR (0.81) | USP2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL3866576 | 0.81 | TSHR (0.55) | CYP3A4CYP2C19CYP2C9TSHRTP53 | |
| SCHEMBL24533635 | 0.79 | CYP3A4 (0.60) | USP2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL18568687 | 0.79 | CYP3A4 (0.54) | USP2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL3867743 | 0.77 | KMT2A (0.59) | USP2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL2354757 | 0.76 | KMT2A (0.58) | USP2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL3872757 | 0.76 | TSHR (0.60) | USP2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL12024152 | 0.75 | HTT (0.58) | USP2CYP3A4CYP2C19CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133237-A2 | METHODS OF TREATING NEURODEGENERATIVE DISORDERS AND STAT3-LINKED CANCERS USING SUPPRESSORS OF ELECTRON LEAK | CORNELL UNIVERSITY (US) | 2022-06-23 | — | — | WO | disclosed |