SCHEMBL3870979

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3866576	0.85	TSHR (0.55)	KMT2AMEN1ALDH1A1NPSR1SMN1; SMN2
	SCHEMBL3872757	0.84	TSHR (0.60)	KMT2AMEN1ALDH1A1NPSR1GAA
	SCHEMBL24533663	0.82	USP2 (0.60)	KMT2AALDH1A1NPSR1GAASMN1; SMN2
	SCHEMBL3890465	0.79	ALDH1A1 (0.62)	ALDH1A1NPSR1GAASMN1; SMN2TP53
	SCHEMBL2357637	0.79	CYP3A4 (0.61)	KMT2AMEN1ALDH1A1NPSR1TP53
	SCHEMBL24533634	0.76	TSHR (0.81)	KMT2AMEN1ALDH1A1NPSR1SMN1; SMN2
	SCHEMBL24533635	0.74	CYP3A4 (0.60)	KMT2AMEN1ALDH1A1NPSR1GAA
	SCHEMBL3867743	0.74	KMT2A (0.59)	KMT2AMEN1ALDH1A1NPSR1SMN1; SMN2
	SCHEMBL2354757	0.73	KMT2A (0.58)	KMT2AMEN1ALDH1A1NPSR1GAA
	SCHEMBL24533631	0.73	TSHR (0.70)	KMT2AMEN1ALDH1A1NPSR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.