Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 4/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.46 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | TYMS | P04818 | 3/20 | 0.45 |
| ▸ | TK1 | P04183 | 2/20 | 0.44 |
| ▸ | TK2 | O00142 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11204766 | 0.92 | DUT (0.57) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL2623789 | 0.90 | DUT (0.55) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL1364671 | 0.89 | DUT (0.61) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL11136389 | 0.87 | DUT (0.61) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL11201697 | 0.86 | DUT (0.60) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL26757491 | 0.85 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL12918449 | 0.85 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL13153886 | 0.85 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL438240 | 0.85 | DUT (0.64) | DUTP2RY2P2RY4P2RY6TYMS | |
| SCHEMBL18670762 | 0.85 | DUT (0.57) | DUTP2RY2P2RY4P2RY6TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133289-A2 | ENGINEERED URIDINE PHOSPHORYLASE VARIANT ENZYMES | CODEXIS, INC. (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022133205-A1 | SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | MERCK SHARP & DOHME CORP. (US) | 2022-06-23 | — | — | WO | disclosed |