SCHEMBL11201697

SCHEMBL11201697

O=C(CCl)OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C[C@@H]1O

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DUT P33316 4/20 0.60
P2RY2 P41231 2/20 0.47
P2RY4 P51582 2/20 0.47
P2RY6 Q15077 1/20 0.47
TYMS P04818 5/20 0.44
SLC28A1 O00337 1/20 0.43
SLC28A2 O43868 1/20 0.43
SLC29A1 Q99808 1/20 0.43
SLC28A3 Q9HAS3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1364671 0.88 DUT (0.61) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL6041222 0.87 DUT (0.58) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL4298071 0.86 DUT (0.64) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL11204766 0.86 DUT (0.57) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL18670762 0.86 DUT (0.57) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL24533744 0.86 DUT (0.59) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL6884089 0.85 DUT (0.56) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL6034461 0.85 DUT (0.66) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL140597 0.85 DUT (0.66) DUTP2RY2P2RY4P2RY6TYMS
SCHEMBL9811623 0.85 DUT (0.61) DUTP2RY2P2RY4P2RY6TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0097039-A1 5-(E-2-halovinyl)-2'-deoxyuridine derivatives, processes for their preparation, pharmaceutical compositions containing them, and their use in treating viral infections BEECHAM GROUP PLC (GB) 1983-12-28 EP disclosed