Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24534564 | 1.00 | MIF (0.60) | MIFESR1ESR2KMT2ANPSR1 | |
| SCHEMBL27181532 | 1.00 | MIF (0.60) | MIFESR1ESR2KMT2ANPSR1 | |
| SCHEMBL27181486 | 0.88 | LDHA (0.51) | MIFKMT2A | |
| SCHEMBL24534585 | 0.88 | LDHA (0.51) | MIFKMT2A | |
| SCHEMBL21594430 | 0.87 | MIF (0.46) | MIFESR1ESR2KMT2A | |
| SCHEMBL20873383 | 0.87 | MIF (0.54) | MIFKMT2ATSHRRAB9AMEN1 | |
| SCHEMBL20873382 | 0.87 | MIF (0.54) | MIFKMT2ATSHRRAB9AMEN1 | |
| SCHEMBL17323076 | 0.87 | MIF (0.54) | MIFKMT2ATSHRRAB9AMEN1 | |
| SCHEMBL14295130 | 0.86 | MIF (0.48) | MIFESR1ESR2KMT2ANPC1 | |
| SCHEMBL24534492 | 0.83 | MIF (0.43) | MIFESR1ESR2RAB9ANLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12522592-B2 | ERAP inhibitors | UNIVERSITE DE LILLE (FR) | 2026-01-13 | — | — | US | disclosed |
| EP-4263533-B1 | ERAP INHIBITORS | UNIV LILLE (FR) | 2025-08-20 | — | — | EP | disclosed |
| US-20240101542-A1 | ERAP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2024-03-28 | — | — | US | disclosed |
| WO-2022129589-A9 | ERAP INHIBITORS | UNIVERSITE DE LILLE (FR) | 2023-08-24 | — | — | WO | disclosed |
| WO-2022129589-A1 | ERAP INHIBITORS | UNIVERSITE DE LILLE (FR) | 2022-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101542-A1 | ERAP INHIBITORS | ERAP2, ERAP1, ERMP1 | MIF 737/4885ESR1 1815/4885ESR2 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.