Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20873382 | 1.00 | MIF (0.54) | MIFPOLBPSMB5PSMB2PSMB1 | |
| SCHEMBL17323076 | 1.00 | MIF (0.54) | MIFPOLBPSMB5PSMB2PSMB1 | |
| SCHEMBL27181642 | 0.89 | PPARG (0.46) | MIFPSMB5PSMB2PSMB1RAB9A | |
| SCHEMBL27181640 | 0.89 | PPARG (0.46) | MIFPSMB5PSMB2PSMB1RAB9A | |
| SCHEMBL24534570 | 0.87 | MIF (0.60) | MIFTSHRKMT2AMEN1RAB9A | |
| SCHEMBL27181532 | 0.87 | MIF (0.60) | MIFTSHRKMT2AMEN1RAB9A | |
| SCHEMBL24534585 | 0.87 | LDHA (0.51) | MIFPSMB5PSMB2PSMB1KMT2A | |
| SCHEMBL27181486 | 0.87 | LDHA (0.51) | MIFPSMB5PSMB2PSMB1KMT2A | |
| SCHEMBL24534564 | 0.87 | MIF (0.60) | MIFTSHRKMT2AMEN1RAB9A | |
| SCHEMBL21594430 | 0.85 | MIF (0.46) | MIFALDH1A1KMT2APPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563056-B | Triazoles for modulating intracellular calcium homeostasis | 巴斯克大学 | 2022-08-16 | — | — | CN | disclosed |
| US-11377427-B2 | Triazoles for regulating intracellular calcium homeostasis | UNIVERSIDAD DEL PAIS VASCO (ES) | 2022-07-05 | — | — | US | disclosed |
| EP-3466933-B1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | UNIV DEL PAIS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) | 2020-12-02 | — | — | EP | disclosed |
| US-20200317625-A1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | UNIVERSIDAD DEL PAIS VASCO (ES) | 2020-10-08 | — | — | US | disclosed |
| EP-3466933-A1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | Universidad del Pais Vasco (ES) | 2019-04-10 | — | — | EP | disclosed |
| CN-109563056-A | For regulating and controlling the triazole of calcium homeostasis intracellular | 巴斯克大学 | 2019-04-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377427-B2 | Triazoles for regulating intracellular calcium homeostasis | RYR1, ATP2A3, RYR2 | MIF 4335/4885POLB 4843/4885PSMB5 2174/4885 |
| US-20200317625-A1 | TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS | RYR1, ATP2A3, RYR2 | MIF 4335/4885POLB 4843/4885PSMB5 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.