SCHEMBL2453590

SCHEMBL2453590

Nc1ccc(C=CS(=O)(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 7/20 0.50
APP P05067 2/20 0.50
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
NT5E P21589 1/20 0.46
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
NQO2 P16083 2/20 0.41
LMNA P02545 2/20 0.39
MPO P05164 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
HTR6 P50406 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL8722674 0.86 CYP19A1 (0.52) CYP19A1TSHRALDH1A1MAOAMAOB
SCHEMBL5713492 0.82 CYP19A1 (0.54) CYP19A1APPTSHRALDH1A1MAOA
SCHEMBL28760348 0.82 CA12 (0.40) CA1LMNACA12CA9TDP1
SCHEMBL10641470 0.80 CYP19A1 (0.52) CYP19A1APPTSHRALDH1A1MAOA
SCHEMBL10641465 0.80 CYP19A1 (0.52) CYP19A1APPTSHRALDH1A1MAOA
SCHEMBL2298614 0.80 APP (0.52) CYP19A1APPALDH1A1MAOAMAOB
SCHEMBL2298611 0.80 APP (0.52) CYP19A1APPALDH1A1MAOAMAOB
SCHEMBL2173890 0.78 LMNA (0.53) ALDH1A1MAOAMAOBCA1CA2
SCHEMBL29496 0.78 TDP1 (0.57) TSHRALDH1A1MAOBCA1CA2
SCHEMBL14297485 0.78 LMNA (0.53) ALDH1A1MAOAMAOBCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8624020-B2 Method for isolating and purifying nucleic acids QIAGEN GMBH (DE) 2014-01-07 US claimed
US-20120130061-A1 Method F Method For Isolating And Purifying Nucleic Acids QIAGEN GMBH (DE) 2012-05-24 US claimed
US-8624020-B2 Method for isolating and purifying nucleic acids QIAGEN GMBH (DE) 2014-01-07 US disclosed
US-20120130061-A1 Method F Method For Isolating And Purifying Nucleic Acids QIAGEN GMBH (DE) 2012-05-24 US disclosed
US-20110224419-A1 Method For Isolating And Purifying Nucleic Acids QIAGEN GMBH (DE) 2011-09-15 US disclosed
CN-101263010-A Coating compositions containing latent catalyst for marking substrates CIBA HOLDING INC (CH) 2008-09-10 CN disclosed