Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 14/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | JAK3 | P52333 | 3/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24535922 | 1.00 | PANK3 (0.47) | PANK3ARRIPK1EGLN1JAK2 | |
| SCHEMBL16478698 | 0.80 | PANK3 (0.46) | PANK3RIPK1JAK2JAK1JAK3 | |
| SCHEMBL16478731 | 0.80 | PANK3 (0.46) | PANK3RIPK1JAK2JAK1JAK3 | |
| SCHEMBL17687600 | 0.78 | PANK3 (0.48) | PANK3RIPK1JAK2JAK1JAK3 | |
| SCHEMBL9920182 | 0.78 | PANK3 (0.44) | PANK3RIPK1JAK2JAK1JAK3 | |
| SCHEMBL18231637 | 0.78 | PANK3 (0.47) | PANK3JAK2JAK1JAK3TYK2 | |
| SCHEMBL12683435 | 0.78 | PANK3 (0.47) | PANK3JAK2JAK1JAK3TYK2 | |
| SCHEMBL12595494 | 0.78 | GLS (0.40) | — | |
| SCHEMBL12683356 | 0.78 | PANK3 (0.47) | PANK3JAK2JAK1JAK3TYK2 | |
| SCHEMBL1977612 | 0.76 | LMNA (0.59) | PANK3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133034-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2022-06-23 | — | — | WO | disclosed |