Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 16/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19748934 | 0.85 | PANK3 (0.50) | PANK3RIPK1TACR3 | |
| SCHEMBL19748933 | 0.85 | PANK3 (0.50) | PANK3RIPK1TACR3 | |
| SCHEMBL31717392 | 0.85 | PANK3 (0.50) | PANK3RIPK1TACR3 | |
| SCHEMBL24536011 | 0.83 | PANK3 (0.52) | PANK3RIPK1CHRM4 | |
| SCHEMBL24535930 | 0.77 | PANK3 (0.67) | PANK3RIPK1 | |
| SCHEMBL24535873 | 0.76 | PANK3 (0.51) | PANK3RIPK1CHRM4 | |
| SCHEMBL26501563 | 0.73 | GLS (0.41) | PANK3 | |
| SCHEMBL21424014 | 0.70 | PANK3 (0.38) | PANK3 | |
| SCHEMBL21423669 | 0.70 | PANK3 (0.51) | PANK3RIPK1 | |
| SCHEMBL31717785 | 0.70 | PANK3 (0.51) | PANK3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133034-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2022-06-23 | — | — | WO | disclosed |