Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12225935 | 0.82 | PTGIR (0.43) | CA12CA2CA9MEN1HTT | |
| SCHEMBL1030304 | 0.78 | LMNA (0.51) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL15998771 | 0.77 | TRPV1 (0.46) | MEN1KMT2ATRPV1 | |
| SCHEMBL3223030 | 0.74 | GBA1 (0.50) | MEN1KMT2ALMNA | |
| SCHEMBL26191736 | 0.72 | TAAR1 (0.40) | HTTCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL24538067 | 0.70 | KDM4E (0.41) | MEN1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL19555128 | 0.69 | TAAR1 (0.39) | CA12CA2CA9CHRM2CHRM4 | |
| SCHEMBL15529292 | 0.69 | KDM4E (0.45) | CA2 | |
| SCHEMBL2081548 | 0.68 | TAAR1 (0.71) | TAAR1 | |
| SCHEMBL24537986 | 0.68 | TAAR1 (0.38) | HTTCHRM2CHRM1LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133083-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2022-06-23 | — | — | WO | disclosed |