Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.49 |
| ▸ | POLRMT | O00411 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17719237 | 0.93 | TMPRSS2 (0.50) | TMPRSS2POLRMTP2RY1SIRT2SIRT1 | |
| SCHEMBL18298281 | 0.92 | TMPRSS2 (0.51) | TMPRSS2POLRMTP2RY1SIRT2SIRT1 | |
| SCHEMBL26326132 | 0.91 | TMPRSS2 (0.49) | TMPRSS2POLRMTP2RY1SIRT2SIRT1 | |
| SCHEMBL20500115 | 0.91 | TMPRSS2 (0.50) | TMPRSS2POLRMTP2RY1SIRT2SIRT1 | |
| SCHEMBL25378413 | 0.91 | TMPRSS2 (0.50) | TMPRSS2POLRMTP2RY1SIRT2SIRT1 | |
| SCHEMBL17719238 | 0.90 | POLRMT (0.48) | TMPRSS2POLRMT | |
| SCHEMBL24917304 | 0.89 | TMPRSS2 (0.47) | TMPRSS2POLRMTP2RY1SRCP2RY2 | |
| Rdv-Tp SCHEMBL24492745 | 0.88 | POLRMT (0.51) | TMPRSS2POLRMTP2RY1 | |
| Rdv-Tp SCHEMBL10120881 | 0.88 | POLRMT (0.51) | TMPRSS2POLRMTP2RY1 | |
| Rdv-Tp SCHEMBL23278555 | 0.88 | POLRMT (0.51) | TMPRSS2POLRMTP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127914-A1 | NUCLEOSIDE-THIODIPHOSPHATE-HEPTOSE COMPOUNDS FOR TREATING CONDITIONS ASSOCIATED WITH ALPK1 ACTIVITY | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2022-06-23 | — | — | WO | disclosed |