Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29733004 | 0.89 | MAPT (0.42) | KDRKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL29601173 | 0.80 | FGFR3 (0.41) | KDRJAK2TYK2JAK1JAK3 | |
| SCHEMBL24327764 | 0.80 | FGFR3 (0.41) | KDRJAK2TYK2JAK1JAK3 | |
| SCHEMBL29732784 | 0.77 | FGFR3 (0.44) | KDRKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL24327855 | 0.76 | LRRK2 (0.58) | LRRK2KDREPHB4TEKMAPK1 | |
| SCHEMBL24327322 | 0.74 | IRAK1 (0.43) | KDREPHB4TEKJAK2TYK2 | |
| SCHEMBL19546 | 0.73 | ADORA2A (0.44) | LRRK2JAK2JAK1JAK3 | |
| SCHEMBL24327260 | 0.72 | LRRK2 (0.45) | LRRK2KDREPHB4TEKNPC1 | |
| SCHEMBL24539484 | 0.71 | JAK2 (0.41) | KDRKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL24327357 | 0.71 | JAK2 (0.39) | KDRKDM4ENPC1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127753-A1 | FUSED RING AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-06-23 | — | — | WO | disclosed |