Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 7/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.38 |
| ▸ | CSF1R | P07333 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 6/20 | 0.35 |
| ▸ | TYK2 | P29597 | 6/20 | 0.35 |
| ▸ | JAK1 | P23458 | 5/20 | 0.35 |
| ▸ | JAK3 | P52333 | 4/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327764 | 1.00 | FGFR3 (0.41) | FGFR3KDRFGFR1FGFR2CSF1R | |
| SCHEMBL24327373 | 0.90 | FGFR3 (0.44) | FGFR3KDRFGFR1FGFR2CSF1R | |
| SCHEMBL29733004 | 0.88 | MAPT (0.42) | FGFR3KDRJAK2TYK2JAK1 | |
| SCHEMBL29498951 | 0.84 | JAK2 (0.48) | FGFR3KDRJAK2TYK2JAK1 | |
| SCHEMBL24539403 | 0.80 | LRRK2 (0.43) | FGFR3KDRFGFR1FGFR2JAK2 | |
| SCHEMBL24327947 | 0.80 | FGFR3 (0.48) | FGFR3KDRFGFR1FGFR2CSF1R | |
| SCHEMBL24327375 | 0.79 | JAK2 (0.40) | FGFR3KDRJAK2TYK2JAK1 | |
| SCHEMBL29498945 | 0.79 | JAK2 (0.35) | FGFR3KDRFGFR1FGFR2JAK2 | |
| SCHEMBL29732784 | 0.76 | FGFR3 (0.44) | FGFR3KDRJAK2TYK2JAK1 | |
| SCHEMBL12594379 | 0.74 | FGFR3 (0.57) | FGFR3KDRCSF1RPIM1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369097-B | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114369097-A | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2022-04-19 | — | — | CN | disclosed |