Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656481 | 0.82 | CES2 (0.56) | CES2CES1ALDH1A1HTTNPSR1 | |
| SCHEMBL23069153 | 0.81 | CES2 (0.58) | CES2CES1ALDH1A1HTTNPSR1 | |
| SCHEMBL146130 | 0.81 | PTPN1 (0.63) | CES2CES1ALDH1A1HTTNPSR1 | |
| Hydrochloric Acid SCHEMBL6744118 | 0.79 | PTPN1 (0.61) | CES2CES1ALDH1A1HTTNPSR1 | |
| SCHEMBL4820037 | 0.79 | CES2 (0.56) | CES2CES1ALDH1A1HTTNPSR1 | |
| SCHEMBL27776787 | 0.78 | CES2 (0.60) | CES2CES1ALDH1A1HTTNPSR1 | |
| SCHEMBL5188791 | 0.78 | CES2 (0.74) | CES2CES1ALDH1A1HTTNPSR1 | |
| SCHEMBL60741 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL31367891 | 0.76 | CES2 (0.62) | CES2CES1ALDH1A1HTTNPSR1 | |
| Hydrogen Sulfide SCHEMBL28650892 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4828407-B2 | — | — | 2011-11-30 | — | — | JP | claimed |
| WO-2007039170-A1 | ANTAGONISTS OF TOPOISOMERASE ACTIVITY AND THEIR USE IN INHIBITING PATHOLOGICAL CONDITIONS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2007-04-12 | — | — | WO | claimed |
| EP-1594869-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | Targacept, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| WO-2004076449-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | TARGACEPT, INC. (US) | 2004-09-10 | — | — | WO | claimed |
| EP-2588521-B1 | CROSS-LINKED POLYOLEFIN COMPOSITION | BASELL POLIOLEFINE SRL (IT) | 2016-10-19 | — | — | EP | disclosed |
| EP-2588524-B1 | CROSS-LINKED POLYOLEFIN COMPOSITION | BASELL POLIOLEFINE SRL (IT) | 2016-01-06 | — | — | EP | disclosed |
| CN-104428331-A | Active energy ray-polymerizable resin composition and laminate obtained using resin composition | TOYO INK SC HOLDINGS CO LTD | 2015-03-18 | — | — | CN | disclosed |
| US-8779063-B2 | Cross-linked polyolefin composition | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-07-15 | — | — | US | disclosed |
| US-8669327-B2 | Cross-linked polyolefin composition | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-03-11 | — | — | US | disclosed |
| EP-2588521-A1 | CROSS-LINKED POLYOLEFIN COMPOSITION | Basell Poliolefine Italia S.r.l. (IT) | 2013-05-08 | — | — | EP | disclosed |
| EP-2588524-A1 | CROSS-LINKED POLYOLEFIN COMPOSITION | Basell Poliolefine Italia S.r.l. (IT) | 2013-05-08 | — | — | EP | disclosed |
| US-20130102735-A1 | Cross-Linked Polyolefin Composition | Basell Poliolefine Italia, s.r.l. (IT) | 2013-04-25 | — | — | US | disclosed |
| EP-0472956-A2 | Dynamically partially crosslinked thermoplastic elastomer containing polybutene-1 | MONTELL NORTH AMERICA INC. (US) | 1992-03-04 | — | — | EP | disclosed |
| US-5082869-A | Homogeneous, flexible | AUSIMONT S.P.A. (IT) | 1992-01-21 | — | — | US | disclosed |
| US-5066700-A | Organic Peroxide Vulcanizing Agent, Furan Derivative As A Crosslinking Coadjuvant | AUSIMONT S.P.A. (IT) | 1991-11-19 | — | — | US | disclosed |
| EP-0450342-A2 | Crosslinked polypropylene compositions suitable for the manufacture of foamed articles | SPHERILENE S.r.l. (IT) | 1991-10-09 | — | — | EP | disclosed |
| US-4963612-A | Plastoelastomeric polyolefinic compositions and process for preparing them according to dynamic vulcanizable methods | AUSIMONT S.R.L. (IT) | 1990-10-16 | — | — | US | disclosed |
| EP-0361205-A2 | Plastoelastomeric polyolefin compositions and process for preparing them | HIMONT ITALIA S.r.l. (IT) | 1990-04-04 | — | — | EP | disclosed |
| US-4906659-A | Antibiotic tan-749, its derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0271829-A2 | Delta-hydroxy-beta-lysine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1988-06-22 | — | — | EP | disclosed |