Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15054395 | 1.00 | TRPM8 (0.55) | TRPM8EPHX1TRPA1CYP19A1TRPV1 | |
| SCHEMBL1603431 | 1.00 | TRPM8 (0.55) | TRPM8EPHX1TRPA1CYP19A1TRPV1 | |
| SCHEMBL12805446 | 0.89 | TRPM8 (0.58) | TRPM8EPHX1TRPA1CYP19A1TRPV1 | |
| SCHEMBL10073499 | 0.89 | TRPM8 (0.58) | TRPM8EPHX1TRPA1CYP19A1TRPV1 | |
| SCHEMBL15857921 | 0.89 | TRPM8 (0.58) | TRPM8EPHX1TRPA1CYP19A1TRPV1 | |
| SCHEMBL14580757 | 0.85 | TRPM8 (0.68) | TRPM8EPHX1TRPA1CYP19A1 | |
| SCHEMBL22460370 | 0.85 | TRPM8 (0.68) | TRPM8EPHX1TRPA1CYP19A1 | |
| SCHEMBL20930061 | 0.85 | TRPM8 (0.68) | TRPM8EPHX1TRPA1CYP19A1 | |
| SCHEMBL14565723 | 0.85 | TRPM8 (0.68) | TRPM8EPHX1TRPA1CYP19A1 | |
| SCHEMBL291020 | 0.85 | TRPM8 (0.68) | TRPM8EPHX1TRPA1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133027-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-06-23 | — | — | WO | disclosed |