Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831089 | 0.94 | FFAR1 (0.46) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL11336506 | 0.81 | BRD4 (0.47) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL3739027 | 0.81 | SRC (0.50) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL664900 | 0.80 | SRC (0.56) | KMT2AMEN1CYP2D6HSD17B10HDAC4 | |
| SCHEMBL5325296 | 0.80 | SRC (0.56) | KMT2AMEN1CYP2D6HSD17B10HDAC4 | |
| SCHEMBL3383072 | 0.79 | LMNA (0.46) | KMT2AMEN1LMNAPOLBCES2 | |
| SCHEMBL3993817 | 0.79 | BRD4 (0.61) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL11307633 | 0.79 | LDHA (0.45) | CYP2C19KMT2AMEN1CYP1A2CES2 | |
| SCHEMBL3070290 | 0.79 | HDAC3 (0.45) | HDAC4HDAC7HDAC5LMNACES2 | |
| SCHEMBL5441902 | 0.79 | BRD4 (0.45) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102603508-B | Preparation method of 1-(4-chlorophenyl)-2-cyclopropyl-1-acetone and intermediate thereof as well as preparation method of intermediate | JIANGSU CHENGYANG CROP TECHNOLOGY CO LTD | 2014-03-12 | — | — | CN | disclosed |
| EP-1853583-B1 | AMINE-LINKED PYRIDYL AND PHENYL SUBSTITUTED PIPERAZINE-PIPERIDINES WITH CXCR3 ANTAGONIST ACTIVITY | SCHERING CORP (US) | 2011-09-07 | — | — | EP | disclosed |
| EP-1456254-B1 | SUPPORTED TITANIUM-CONTAINING CATALYST FOR HOMO-, CO-, AND TER-POLYMERIZATION OF OLEFINS | POLIMERI EUROPA SPA (IT) | 2010-03-24 | — | — | EP | disclosed |
| US-7449528-B2 | Supported catalyst containing active titanium in the homo, co-, and ter-polymerization of olefin-unsaturated compounds | POLIMERI EUROPA S.P.A. (IT) | 2008-11-11 | — | — | US | disclosed |
| US-20060014631-A1 | Supported catalyst containing active titanium in the homo, co-, and ter-polymerization of olefin-unsaturated compounds | POLIMERI EUROPA S.P.A. (IT) | 2006-01-19 | — | — | US | disclosed |
| EP-1456254-A2 | SUPPORTED TITANIUM-CONTAINING CATALYST FOR HOMO-, CO-, AND TER-POLYMERIZATION OF OLEFINS | Polimeri Europa S.p.A. (IT) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003054034-A2 | SUPPORTED TITANIUM-CONTAINING FOR HOMO-, CO-, AND TER-POLYMERIZATION OF OLEFINS | POLIMERI EUROPA S.P.A. (IT) | 2003-07-03 | — | — | WO | disclosed |
| US-4627874-A | RICE PRODUCTION | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1986-12-09 | — | — | US | disclosed |
| US-4455164-A | HALOGENATED DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1984-06-19 | — | — | US | disclosed |