SCHEMBL2454243

SCHEMBL2454243

O=C(C1=CCC(c2ccccc2)(c2ccccc2)C=C1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SRD5A2 P31213 1/20 0.36
VNN1 O95497 1/20 0.35
HPGDS O60760 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
AKR1C3 P42330 1/20 0.34
LMNA P02545 3/20 0.33
HDAC4 P56524 1/20 0.33
F2 P00734 1/20 0.33
CYP2C8 P10632 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPT P10636 3/20 0.33
RAB9A P51151 2/20 0.33
TSHR P16473 2/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27537948 0.86 KMT2A (0.37) L3MBTL1ATMTDP1MEN1KMT2A
SCHEMBL29034394 0.83 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL27893123 0.83 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL993046 0.80 ALDH1A1 (0.43) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL136599 0.80 ALDH1A1 (0.43) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL659657 0.79 ALDH1A1 (0.42) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL156513 0.79 ALDH1A1 (0.42) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL1303037 0.79 ALDH1A1 (0.42) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL528382 0.79 ALDH1A1 (0.42) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL2470211 0.79 ALDH1A1 (0.42) ALDH1A1L3MBTL1ATMTDP1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023005682-A1 METHOD FOR ANALYZING TARGETED EXPOSURE GROUP OF ENVIRONMENTAL POLLUTANTS IN PLASMA, AND USE THEREOF 暨南大学 2023-02-02 WO disclosed
CN-110521290-A Photosensitive resin composition, dry film using same, printed wiring board, and method for producing printed wiring board HITACHI CHEMICAL CO LTD 2019-11-29 CN disclosed
EP-2862012-A1 (METH)ACRYLATE COMPOUND, OPTICAL COMPOSITION, MOLDED ARTICLE, AND OPTICAL ELEMENT Canon Kabushiki Kaisha (JP) 2015-04-22 EP disclosed
WO-2014021355-A1 (METH)ACRYLATE COMPOUND, OPTICAL COMPOSITION, MOLDED ARTICLE, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2014-02-06 WO disclosed
WO-2011118541-A1 CONJUGATED AROMATIC COMPOUND, OPTICAL MATERIAL, AND OPTICAL ELEMENT CANON KABUSHIKI KAISHA (JP) 2011-09-29 WO disclosed
US-4788206-A CARDIOVASCULAR DISORDERS, PLATELETS HOFFMANN-LA ROCHE INC. (US) 1988-11-29 US disclosed