SCHEMBL659657

SCHEMBL659657

O=C(C1=CCC(Br)(Br)C=C1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
SRD5A2 P31213 1/20 0.37
HPGDS O60760 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
AKR1C3 P42330 1/20 0.35
CYP2C8 P10632 1/20 0.34
CYP2C9 P11712 1/20 0.34
MAPT P10636 3/20 0.33
TSHR P16473 2/20 0.33
LMNA P02545 2/20 0.33
RAB9A P51151 2/20 0.33
ALOX15 P16050 2/20 0.33
DAO P14920 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2942183 0.87 ALDH1A1 (0.40) ALDH1A1L3MBTL1ATMSRD5A2MEN1
SCHEMBL11743114 0.85 ALDH1A1 (0.41) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL27480528 0.85 ALDH1A1 (0.41) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL830474 0.85 CES2 (0.45) ALDH1A1L3MBTL1ATMMAPTTSHR
SCHEMBL7423422 0.84 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL28642593 0.84 ALDH1A1 (0.39) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL993046 0.81 ALDH1A1 (0.43) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL136599 0.81 ALDH1A1 (0.43) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL3041974 0.80 ALDH1A1 (0.36) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL27550913 0.80 ALDH1A1 (0.36) ALDH1A1L3MBTL1ATMTDP1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126282-A Amphoteric block copolymer and preparation method and application thereof 河北工业大学 2024-06-04 CN claimed
CN-116333458-B High-temperature-resistant biodegradable agricultural film for rice based on graphene and multiwall carbon nanotube composite material 大禾科技发展(南京)有限公司 2023-12-01 CN claimed
CN-114369103-B Perylene diimide electron acceptor material with ether structure as core, and preparation method and application thereof 中山大学 2023-10-17 CN claimed
CN-116333458-A High-temperature-resistant biodegradable agricultural film for rice based on graphene and multiwall carbon nanotube composite material 大禾科技发展(南京)有限公司 2023-06-27 CN claimed
CN-113651907-B Side chain type aggregation-induced emission liquid crystal polymer with periodic structure and preparation method thereof 大连理工大学 2023-03-24 CN claimed
CN-114369103-A Perylene diimide electron acceptor material with ether structure as core, preparation method and application thereof 中山大学 2022-04-19 CN claimed
CN-106814057-B A kind of fluorescence probe, synthetic method and its application being used for Selective recognition ATP based on aggregation inducing fluorescence enhancement characteristic 赣南师范大学 2019-07-16 CN claimed
CN-106814057-A A kind of fluorescence probe, synthetic method and its application for being used for Selective recognition ATP based on aggregation inducing Fluorescence Increasing characteristic 赣南师范大学 2017-06-09 CN claimed
CN-118126282-A Amphoteric block copolymer and preparation method and application thereof 河北工业大学 2024-06-04 CN disclosed
CN-115404721-B Preparation and application of photoresponse thermal printing paper 西北工业大学 2024-04-26 CN disclosed
CN-116333458-B High-temperature-resistant biodegradable agricultural film for rice based on graphene and multiwall carbon nanotube composite material 大禾科技发展(南京)有限公司 2023-12-01 CN disclosed
CN-114369103-B Perylene diimide electron acceptor material with ether structure as core, and preparation method and application thereof 中山大学 2023-10-17 CN disclosed
CN-114957692-B Hyperbranched polyphenyl and preparation method and application thereof 苏州大学 2023-08-11 CN disclosed
CN-116333458-A High-temperature-resistant biodegradable agricultural film for rice based on graphene and multiwall carbon nanotube composite material 大禾科技发展(南京)有限公司 2023-06-27 CN disclosed
US-20040143006-A1 Novel compounds, their preparation and use HIGH POINT PHARMACEUTICALS, LLC 2004-07-22 US disclosed
EP-0900237-A1 PHOTOACTIVE COMPOUNDS FOR USE WITH NARROW WAVELENGTH BAND ULTRAVIOLET (UV) CURING SYSTEMS First Chemical Corporation (US) 1999-03-10 EP disclosed
WO-1998000385-A1 PROCESS FOR PRODUCING BENZOPHENONE COMPOUNDS ALLIEDSIGNAL INC. (US) 1998-01-08 WO disclosed
WO-1997044364-A1 PHOTOACTIVE COMPOUNDS FOR USE WITH NARROW WAVELENGTH BAND ULTRAVIOLET (UV) CURING SYSTEMS FIRST CHEMICAL CORPORATION (US) 1997-11-27 WO disclosed
EP-0296877-A2 Poly(arylene thioetherketone)compositions improved in both melt stability and crystallinity KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-12-28 EP disclosed
US-4297433-A MIXTURE WITH 4,4*-DIBROMOBENZOPHENONE; PHOTORESISTS; PHOTOLITHOGRAPHY TOKYO OHKA KOGYO KABUSHIKI KAISHA (JP) 1981-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040143006-A1 Novel compounds, their preparation and use PPARG, PPARD, PPARA ALDH1A1 722/4885L3MBTL1 4856/4885ATM 3862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.