Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24543016 | 0.91 | PPARA (0.51) | PPARACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24542787 | 0.90 | PPARA (0.50) | PPARACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24542755 | 0.89 | CYP1A2 (0.60) | PPARACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24542758 | 0.89 | PPARA (0.52) | PPARACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24542785 | 0.89 | PPARA (0.49) | PPARACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24542753 | 0.89 | PPARA (0.57) | PPARACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24543063 | 0.88 | PPARA (0.54) | PPARACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24543070 | 0.87 | ALDH1A1 (0.48) | PPARACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24543043 | 0.87 | PPARA (0.47) | PPARACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL24543299 | 0.87 | PPARA (0.54) | PPARACYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129933-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | Pandeia Therapeutics Limited (GB) | 2022-06-23 | — | — | WO | disclosed |