Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.54 |
| ▸ | PPARD | Q03181 | 5/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MDH1 | P40925 | 1/20 | 0.43 |
| ▸ | MDH2 | P40926 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24542758 | 0.88 | PPARA (0.52) | PPARAPPARDPPARGLMNACYP1A2 | |
| SCHEMBL24543016 | 0.88 | PPARA (0.51) | PPARAPPARDPPARGLMNACYP1A2 | |
| SCHEMBL24543029 | 0.87 | PPARA (0.50) | PPARACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL24542787 | 0.87 | PPARA (0.50) | PPARALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24543049 | 0.87 | KIF11 (0.45) | PPARAPPARDPPARGLMNAHTT | |
| SCHEMBL24542755 | 0.86 | CYP1A2 (0.60) | PPARACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL24542785 | 0.86 | PPARA (0.49) | PPARALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24542753 | 0.86 | PPARA (0.57) | PPARAPPARGCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24543063 | 0.85 | PPARA (0.54) | PPARALMNAHTTCYP1A2CYP3A4 | |
| SCHEMBL24542766 | 0.84 | TRPV1 (0.54) | PPARAPPARDPPARGTRPV1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132450-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA PHARMACEUTICALS INC. | 2024-04-25 | — | — | US | disclosed |
| WO-2022129933-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | Pandeia Therapeutics Limited (GB) | 2022-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132450-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | GPR88, GPR65, GPR68 | PPARA 355/4885PPARD 408/4885PPARG 186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.