SCHEMBL2454313

SCHEMBL2454313

C[C@H]1OC(OC2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 0.78

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ AMY1A P0DUB6 1/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ MAPT P10636 1/20 0.49
▸ SELE P16581 1/20 0.48
▸ PTPN1 P18031 1/20 0.48
▸ STAT3 P40763 4/20 0.46
▸ SYNJ2 O15056 1/20 0.46
▸ GAA P10253 1/20 0.45
▸ TYR P14679 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4265622 1.00 AMY1A (0.55) AMY1AL3MBTL1MEN1KMT2AMAPT
SCHEMBL17072443 1.00 AMY1A (0.55) AMY1AL3MBTL1MEN1KMT2AMAPT
SCHEMBL6914548 1.00 AMY1A (0.55) AMY1AL3MBTL1MEN1KMT2AMAPT
SCHEMBL1096608 1.00 AMY1A (0.55) AMY1AL3MBTL1MEN1KMT2AMAPT
SCHEMBL7545171 1.00 AMY1A (0.55) AMY1AL3MBTL1MEN1KMT2AMAPT
SCHEMBL301721 1.00 AMY1A (0.55) AMY1AL3MBTL1MEN1KMT2AMAPT
SCHEMBL10620884 1.00 AMY1A (0.55) AMY1AL3MBTL1MEN1KMT2AMAPT
SCHEMBL17072438 1.00 AMY1A (0.55) AMY1AL3MBTL1MEN1KMT2AMAPT
SCHEMBL9939094 1.00 AMY1A (0.55) AMY1AL3MBTL1MEN1KMT2AMAPT
SCHEMBL29572443 1.00 AMY1A (0.55) AMY1AL3MBTL1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5993889-A A D-GLUCOSYL-TRANSFERRED SACCHARIDE, SAID COMPOSITION ALSO CONTAINING PORTIONS OF BETA-D-GLUCOSE-1-PHOSPORHIC ACID ITS SALT OR A MIXTURE THEREOF, AND ANOTHER SACCHARIDE KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1999-11-30 — — US claimed
US-20120258043-A1 Linkable Lewis X Analogs BRACCO SUISSE S.A. (CH) 2012-10-11 — — US disclosed
US-20110229409-A1 LINKABLE LEWIS X ANALOGS BRACCO INTERNATIONAL B.V. (NL) 2011-09-22 — — US disclosed
US-20080300220-A1 Linkable Lewis X Analogs BRACCO INTERNATIONAL B.V. (NL) 2008-12-04 — — US disclosed
US-7422733-B2 Linkable sialyl Lewis X analogs BRACCO INTERNATIONAL B.V. (NL) 2008-09-09 — — US disclosed
EP-0841397-B1 Trehalose phosphorylase, its preparation and uses HAYASHIBARA BIOCHEM LAB (JP) 2006-01-18 — — EP disclosed
US-20040097403-A1 Linkable sialyl lewis x analogs BRACCO SUISSE SA (CH) 2004-05-20 — — US disclosed
EP-1337539-A2 LINKABLE SIALYL LEWIS X ANALOGS BRACCO INTERNATIONAL B.V. (NL) 2003-08-27 — — EP disclosed
WO-2002062810-A2 LINKABLE SIALYL LEWIS X ANALOGS BRACCO INTERNATIONAL B.V. (NL) 2002-08-15 — — WO disclosed
US-5993889-A A D-GLUCOSYL-TRANSFERRED SACCHARIDE, SAID COMPOSITION ALSO CONTAINING PORTIONS OF BETA-D-GLUCOSE-1-PHOSPORHIC ACID ITS SALT OR A MIXTURE THEREOF, AND ANOTHER SACCHARIDE KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1999-11-30 — — US disclosed
US-5910436-A CULTURE PRODUCT KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1999-06-08 — — US disclosed
US-5876975-A CONTACTING TREHALOSE PHOSPHORYLASE OBTAINED FROM THERMOANAEROBIUM GENUS WITH BETA-D-GLUCOSE-1-PHOSPHORIC ACID AND ANOTHER SACCHARIDE TO PRODUCE D-GLUCOSYL-TRANSFERRED SACCHARIDE KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1999-03-02 — — US disclosed
US-5843748-A Trehalose phosphorylase its preparation and uses KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1998-12-01 — — US disclosed
WO-1998030572-A1 PROCESSES FOR THE PREPARATION OF αGal(1→4)βGal(1→4)Glc-OR SYNSORB BIOTECH, INC. (CA) 1998-07-16 — — WO disclosed
EP-0841397-A2 Trehalose phosphorylase, its preparation and uses KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) 1998-05-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300220-A1 Linkable Lewis X Analogs SSB, SELPLG, SELL AMY1A 3697/4885L3MBTL1 555/4885MEN1 1604/4885
US-20120258043-A1 Linkable Lewis X Analogs SSB, SELPLG, SELL AMY1A 3697/4885L3MBTL1 555/4885MEN1 1604/4885
US-20040097403-A1 Linkable sialyl lewis x analogs SSB, SELPLG, SELL AMY1A 3507/4885L3MBTL1 670/4885MEN1 1637/4885
US-20110229409-A1 LINKABLE LEWIS X ANALOGS SELPLG, SELL, SELE AMY1A 2253/4885L3MBTL1 490/4885MEN1 2549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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