SCHEMBL2454355

SCHEMBL2454355

CCCCNc1c(C#N)c(C#N)c(F)c(Sc2ccccc2)c1Sc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 4/20 0.33
ABCB1 P08183 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
BCL2 P10415 1/20 0.32
BCL2L1 Q07817 1/20 0.32
MCL1 Q07820 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
ACP1 P24666 1/20 0.32
CACNA2D1 P54289 1/20 0.32
ALOX15 P16050 1/20 0.31
LMNA P02545 2/20 0.31
PAX8 Q06710 1/20 0.31
BCHE P06276 1/20 0.31
TRPC3 Q13507 1/20 0.31
TRPC4 Q9UBN4 1/20 0.31
TRPC5 Q9UL62 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2455421 0.86 GAA (0.36) MAOAMAOBBCHEKDM4EALDH1A1
SCHEMBL2454751 0.85 KDM4E (0.34) SLC2A1ABCB1ABCG2BCL2BCL2L1
SCHEMBL2455396 0.81 HPGD (0.39) MAOAMAOBLMNAKDM4EALDH1A1
SCHEMBL7106251 0.78 MAOA (0.48) MCL1L3MBTL1MAOAMAOBLMNA
SCHEMBL2454063 0.78 CYP1A2 (0.34) CYP1A2CYP3A4
SCHEMBL27622759 0.77 BCL2 (0.38) SLC2A1ABCB1ABCG2BCL2BCL2L1
SCHEMBL2453615 0.77 ADORA1 (0.37) L3MBTL1MAOAMAOBLMNAADORA2A
SCHEMBL2453469 0.74 ALDH1A1 (0.39) LMNAKDM4EALDH1A1HPGD
SCHEMBL2453573 0.72 MAPT (0.38) MAOAMAOBLMNABCHEKDM4E
SCHEMBL7869250 0.72 CA12 (0.49) MCL1L3MBTL1MAOAMAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1577350-B1 Method for production of halogen-containing phthalocyanine compound NIPPON CATALYTIC CHEM IND (JP) 2011-09-14 EP disclosed
US-7473777-B2 Method for production of halogen-containing phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 2009-01-06 US disclosed
EP-1577350-A1 Method for production of halogen-containing phthalocyanine compound Nippon Shokubai Co., Ltd. (JP) 2005-09-21 EP disclosed
US-20050203293-A1 Method for production of halogen-containing phthalocyanine compound NIPPON SHOKUBAI CO., LTD. (JP) 2005-09-15 US disclosed