SCHEMBL2454510

SCHEMBL2454510

CC(C)C(O)C(C)(C)COCCO

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.36
TSHR P16473 2/20 0.36
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20016191 0.96 MEN1 (0.42) TRPA1TSHRMAPK1ALDH1A1MEN1
Triethylene Glycol SCHEMBL8539657 0.82 MEN1 (0.44) TRPA1TSHRMAPK1ALDH1A1MEN1
SCHEMBL28862322 0.80 TSHR (0.41) TSHRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL15361787 0.80 TSHR (0.39) TRPA1TSHRMEN1KMT2A
SCHEMBL20016189 0.80 HSD17B10 (0.42) TRPA1
SCHEMBL4398227 0.78 TRPA1 (0.38) TRPA1TSHRMAPK1
SCHEMBL4402881 0.77 TRPA1 (0.37) TRPA1MAPK1
SCHEMBL5175834 0.76 USP2 (0.39) TRPA1
SCHEMBL4405273 0.73 TRPA1 (0.35) TRPA1
SCHEMBL10869841 0.72 TSHR (0.33) TSHRMAPK1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2365958-A2 METHOD FOR PRODUCING 2,2,4-TRIMETHYL-1,3-PENTANEDIOL DI-2-ETHYLHEXANOATE Eastman Chemical Company (US) 2011-09-21 EP claimed
WO-2010074703-A2 METHOD FOR PRODUCING 2,2,4-TRIMETHYL-1,3-PENTANEDIOL DI-2-ETHYLHEXANOATE EASTMAN CHEMICAL COMPANY (US) 2010-07-01 WO claimed
US-7674931-B1 Method for producing 2,2,4-trimethyl-1,3-pentanediol di-2-ethylhexanoate EASTMAN CHEMICAL COMPANY (US) 2010-03-09 US claimed
EP-2365958-A2 METHOD FOR PRODUCING 2,2,4-TRIMETHYL-1,3-PENTANEDIOL DI-2-ETHYLHEXANOATE Eastman Chemical Company (US) 2011-09-21 EP disclosed
WO-2010074703-A2 METHOD FOR PRODUCING 2,2,4-TRIMETHYL-1,3-PENTANEDIOL DI-2-ETHYLHEXANOATE EASTMAN CHEMICAL COMPANY (US) 2010-07-01 WO disclosed
US-7674931-B1 Method for producing 2,2,4-trimethyl-1,3-pentanediol di-2-ethylhexanoate EASTMAN CHEMICAL COMPANY (US) 2010-03-09 US disclosed