Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569561 | 0.87 | MEN1 (0.61) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL20016191 | 0.86 | MEN1 (0.42) | MEN1KMT2ATSHRMAPK1THRB | |
| Ethylene Glycol SCHEMBL28152293 | 0.83 | TRPA1 (0.42) | TSHRTRPA1ALDH1A1PTGS1KCNH2 | |
| Ethylene Glycol SCHEMBL2832859 | 0.83 | TRPA1 (0.42) | TSHRTRPA1ALDH1A1PTGS1KCNH2 | |
| SCHEMBL19645 | 0.82 | TRPA1 (0.45) | TSHRMAPK1TRPA1ALDH1A1PTGS1 | |
| SCHEMBL17072023 | 0.82 | TRPA1 (0.45) | TSHRMAPK1TRPA1ALDH1A1PTGS1 | |
| SCHEMBL20721697 | 0.82 | TRPA1 (0.45) | TSHRMAPK1TRPA1ALDH1A1PTGS1 | |
| SCHEMBL2454510 | 0.82 | TRPA1 (0.36) | MEN1KMT2ATSHRMAPK1TRPA1 | |
| SCHEMBL15361789 | 0.81 | TSHR (0.47) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL10818718 | 0.80 | TRPA1 (0.43) | TSHRTRPA1ALDH1A1PTGS1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852162-A | Low molecular weight hydroxy functional polyesters for coatings | MORTON INTERNATIONAL, INC. (US) | 1998-12-22 | — | — | US | disclosed |